Description
Buy 4-AcO-DMT Online
Discover the cutting edge of psychedelic research with 4-AcO-DMT—a synthetic tryptamine renowned for its profound hallucinogenic effects and structural similarity to psilocybin, the active compound in magic mushrooms. Also known as psilacetin, 4-acetoxy-DMT, or O-acetylpsilocin, this compound is a prodrug of psilocin and is metabolized by the body to produce effects closely resembling those of psilocybin mushrooms.
Product Highlights
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Synonym Name: Psilacetin, 4-acetoxy-dimethyltryptamine, O-Acetylpsilocin
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Chemical Name: 4-acetoxy-N,N-dimethyltryptamine
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CAS Number: Multiple including 2748484-99-1 (hydrochloride), 92292-84-7, and 1217230-42-6 (fumarate)
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Molecular Formula: C₁₄H₁₈N₂O₂
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Molecular Weight: 246.3 g/mol
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Available Forms: Available as an analytical reference standard in hydrochloride, fumarate, and freebase forms
Product Overview
4-AcO-DMT (4-acetoxy-N,N-dimethyltryptamine) is a semi-synthetic tryptamine closely related to the psychoactive molecules psilocin and psilocybin found in magic mushrooms. Like psilocybin, it is believed to be a prodrug for psilocin, meaning it is metabolized in the body to produce the active psychedelic effects.
Key Features
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Analytical Reference Standard: High-purity material designed for research and forensic applications
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Prodrug Profile: Provides approximately 70% peripheral psilocin exposure compared to equimolar psilocybin, enabling refined dose-response research designs
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Research Applications: Used in pharmacological studies investigating serotonergic psychedelics, prodrug deacetylation mechanisms, and behavioral models
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High Purity: Supplied at ≥98% purity in various standard pack sizes
Chemical & Pharmacological Properties
4-AcO-DMT acts as a partial agonist at serotonin 5-HT2A receptors, which are responsible for the hallmark psychedelic effects of this compound. It also demonstrates affinity for other serotonin receptors, including 5-HT1A, 5-HT2B, and 5-HT2C, contributing to its complex pharmacological profile.
The compound is thermally stable at 200°C under GC and has 15 characterized metabolites, including biomarker M2-1, which can help differentiate ingestion of psilocybin and psilocin in research settings.
How to Use in Research
4-AcO-DMT is typically supplied as a dry powder or waxy solid that can be dissolved in appropriate solvents such as DMF, DMSO, ethanol, or PBS for research applications.
Recommended Handling:
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Storage: Store stock solutions below -20°C for long-term stability
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Solubility: Warm the tube at 37°C and shake in an ultrasonic bath for improved dissolution
Legal & Safety Information
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Legal Status: While not explicitly scheduled under the U.S. Federal Controlled Substances Act, 4-AcO-DMT is considered an analog of psilocin and may be subject to the Federal Analogue Act. It is classified as a narcotic in some countries, including France
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Research Use Only: This product is strictly for non-human research and forensic applications. Not for human consumption or therapeutic use
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International Control: The UNODC has identified 4-AcO-DMT as a synthetic tryptamine reported as a new psychoactive substance, and it may be controlled at the national level in various countries.
Advance your psychedelic research—add 4-AcO-DMT to your laboratory’s inventory today and explore the frontiers of serotonergic pharmacology.
